Cobetter Minilab TFF Tangential Flow Filtration System

In the initial stage of process development, pharmaceutical companies often have the following pain points, considering factors such as R&D costs, laboratory conditions, process uncertainty, and future process transfer:

• High experimental operation requirements and low error tolerance rate;
• System automation is low;
• Data collection is difficult and the amount of data is small;
• Process testing costs are high;
• Yield is difficult to control and reproducibility is poor

Cobetter took this as its original design intention and focused on solving many problems encountered in R&D testing. It developed and designed the Minilab small TFF ultrafiltration system to better support the R&D process of pharmaceutical companies.

Features

• Small running volume and low testing cost; can be freely and flexibly matched;
• Can be adapted to two types of consumables: hollow fiber membrane or membrane cassette;
• Can match a variety of different brand products;
• Powerful function, can realize a variety of process operations;
• A variety of data can be collected and recorded;
• Suitable for basic process development at the R&D end

Components

Minilab TFF system has the characteristics of free combination and flexible matching, and can adapt to various complex usage environments of clients. Its system components include the following parts.

Figure: Cobetter Minilab TFF Tangential Flow Filtration System

System Functions

Constant TMP control;
Constant ∆P control;
NWP calculation;
Continuous/discontinuous concentration;
Shear rate calculation;
Recipe management;
Batch management/report management;
Data processing/data export/trend analysis;
Equal volume filtration

System Parameters