Home Products Industrial Liquid Filter Cartridges DN66PC/N66PC Sterilizing-Grade Liquid Filter

DN66PC/N66PC Sterilizing-Grade Liquid Filter

Cobetter DN66PC/N66PC series filter cartridges are made of naturally hydrophilic nylon 66 membranes, which are modified with positively-charged N66 membranes to absorb and remove particles, bacteria and endotoxins that are smaller than the filter pore size.

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Description Specifications Ordering Information

Description

Features

Naturally hydrophilic
The use of modified positively-charged N66 membranes removes endotoxins from water, absorbing particles and endotoxins smaller than the filter membrane pore size.
Good integrity and high bubble point values ensure excellent sterilization and particle removal efficiency
Low pressure drop, high flow rates, long-life

Applications

Sterile filtration for LVP, SVP and antibiotic solutions
Sterile filtration of saline and other solvents
Filtration of pharmaceutical water and removal of pyrogens
Pharmaceutical sterile filtration
Solvent filtration
Alkaline solution filtration

Quality

100% Integrity testing in manufacturing
Each filter is fully traceable with unique serial number
Manufactured in a facility which adheres to ISO 9001:2015 Practices

Evaluation of Endotoxin Absorption Efficiency

Flow Rate Characteristics

Specifications

Materials of Construction

Membrane	Nylon 66
Support	Polypropylene (PP), polyester (PET)
Core/Cage/End Caps	Polypropylene (PP)
End Cap Inserts	Polybutylene terephthalate (PBT)
Seal Material	Silicone / EPDM / Viton FEP/ PFA encapsulated O-rings

Operating Conditions

Max. Operating Temperature	80°C
Max.Operating Pressure	0.69 MPa@25°C 0.40 MPa@60°C 0.24 MPa@80°C
Max. Differential Pressure (Forward)	0.69 MPa@25°C 0.40 MPa@60°C 0.24 MPa@80°C
Max. Differential Pressure (Reverse)	0.30 MPa@25°C 0.10 MPa@80°C

Filtration Area

	Outer Diameter	Membrane Pore Size	Area/10"
DN66PC	69 mm	0.22+0.22 μm	0.58 m²
	69 mm	0.45+0.22 μm	0.68 m²
	71 mm	0.45+0.22 μm	0.82 m²
	69 mm	1.2+0.45 μm	0.84 m²
N66PC	69 mm	0.22 μm	0.65 m²

Integrity Test Standards @10inch，20°C (DN66PC)

Membrane Pore Size	Bubble Point	Air Diffusion
0.22+0.22 μm	≥ 0.30 MPa (water), Air test	≤ 16 ml/min @ 0.275 MPa (water)
0.45+0.22 μm(outer diameter 69mm)	≥ 0.30 MPa (water), Air test	≤ 20 ml/min @ 0.275 MPa (water)
0.45+0.22 μm(outer diameter 71mm)	≥ 0.30 MPa (water), Air test	≤ 24 ml/min @ 0.275 MPa (water)
1.2+0.45 μm	≥ 0.12 MPa (water), Air test	≤ 18 ml/min @ 0.1 MPa (water)

Integrity Test Standards @10inch，20°C (N66PC)

Membrane Pore Size	Bubble Point	Air Diffusion
0.22 μm	≥ 0.30 MPa, Wetted with water, Air test	/

Bacterial Retention

Model	Content
69DN66PC 0.22+0.22 μm	Bacterial quantitative retention of 10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) accordingto ASTM F838 methodology.
69DN66PC 0.45+0.22 μm
71DN66PC 0.45+0.22 μm
69DN66PC 1.2+0.45 μm	Bacterial quantitative retention of 10⁷ cfu/cm² Serratia marcescens (ATCC14756) according to ASTM F838 methodology
N66PC 0.22 μm	Bacterial quantitative retention of 10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) accordingto ASTM F838 methodology.

Sterilization

In-line steam sterilization

Up to 10 cycles (121 °C for 30 minutes and differential pressure <30KPa per cycle )

Regulatory Compliance

Autoclaved filter effluent meets the USP<788> requirement of particulate matter in large volume injection.
Component materials meet the criteria for a "Non-fiber-releasing filter" as defined in 21 CFR 210.3(b)(6).
Aqueous extraction from a cartridge contains less than 0.25EU/ml as determined by Limulus Amebocyte Lysate (LAL), meeting requirements of USP<85>.
Meet the requirement of USP <87> In Vitro Cytotoxicity Test.
Component materials meet the requirements of the current USP<88> for plastic class VI-121°C.
All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182.
Based on the current information from our suppliers, all component materials used in the manufacture of this product are animal-free.

End Cap

Ordering Information

DN66PC (Double-layer)

Outer Diameter	Type	Membrane Pore Size	End Cap	Nominal Length	Seal Material	Industry
69mm	DN66PC	0022 0.22 µm	DOE Double Open End	05 5 inch	S Silicone	P
71 71mm		2222 0.22+0.22 µm	HTF 222/Fin (PBT insert)	10 10 inch	E EPDM
		4522 0.45+0.22 µm	HSF 226/Fin (PBT insert)	20 20 inch	V Viton
		1245 1.2+0.45 µm	HTCG 222/Flat (PBT insert)	30 30 inch	P FEP/PFA encapsulated O-rings
			HSCG 226/Flat (PBT insert)	40 40 inch

N66PC (Single-layer)

Outer Diameter	Type	Membrane Pore Size	End Cap	Nominal Length	Seal Material	Industry
69mm	N66PC	0022 0.22 µm	DOE Double Open End	05 5 inch	S Silicone	P
71 71mm		0045 0.45 μm	HTF 222/Fin (PBT insert)	10 10 inch	E EPDM
		0120 1.2 μm	HSF 226/Fin (PBT insert)	20 20 inch	V Viton
			HTCG 222/Flat (PBT insert)	30 30 inch	P FEP/PFA encapsulated O-rings
			HSCG 226/Flat (PBT insert)	40 40 inch

* Example：DN66PC2222DOE05SP (DN66PC，0.22+0.22µm，Double open end，5 inch，Silicone，Pharmaceutical)